Organ Specification-Growth Control Connection: New In-Sights From the Drosophila Eye-Antennal Disc

Dev Dyn. 2005 Mar;232(3):673-84. doi: 10.1002/dvdy.20311.

Abstract

The eye-antennal disc of Drosophila is serving a guiding role in the studies of how eye identity is specified, as well as how the retina is patterned. However, this system also holds a great potential for studying the coordination between organ growth and specification when various distinct organs form from a common primordium. The eye-antennal disc gives origin not only to the compound eye but also to the head capsule, ocelli, maxillary palp, and antenna, and these organs develop bearing constant size proportions with each other. Here, we review recent results that have shed light on the mechanisms that control the specification and growth of organs of the eye-antennal disc and discuss how these controls are intertwined during the development of neighboring organs to ensure their constant shape and relative sizes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biological Evolution
  • Drosophila / embryology*
  • Drosophila / genetics*
  • Drosophila / metabolism
  • Drosophila Proteins / genetics
  • Embryo, Nonmammalian
  • Embryonic Induction
  • Eye / embryology*
  • Eye / ultrastructure
  • Female
  • Gene Expression Regulation, Developmental*
  • Genes, Insect
  • Head / anatomy & histology
  • Head / embryology
  • Humans
  • Larva
  • Metamorphosis, Biological
  • Models, Biological
  • Morphogenesis
  • Optic Disk / embryology*
  • Organ Specificity

Substances

  • Drosophila Proteins