Three-dimensional echocardiographic volume computation by polyhedral surface reconstruction: in vitro validation and comparison to magnetic resonance imaging

J Am Soc Echocardiogr. Mar-Apr 1992;5(2):115-24. doi: 10.1016/s0894-7317(14)80541-5.


Two-dimensional echocardiographic methods of left ventricular volume computation are limited by geometric assumptions and image plane positioning error in the nonvisualized dimension. We evaluated a three-dimensional (3D echocardiographic method that addresses these limitations. Our method uses a volume computation algorithm based on polyhedral surface reconstruction (PSR) and nonparallel, unequally spaced, nonintersecting short-axis planes. Seventeen balloon phantoms were subjected to volume computation by the 3D echocardiography-PSR method and by magnetic resonance imaging (MRI) and compared to true volumes determined by water displacement. The results for 3D echocardiography-PSR were: accuracy = 2.27%, interobserver variability = 4.33%, r = 0.999, SEE = 2.45 ml, and p less than 0.001. Results for MRI were 8.01%, 13.78%, r = 0.995, SEE = 7.01 ml, and p less than 0.001. There was no statistically significant difference between the methods. We conclude that precise image plane positioning and use of the 3D echocardiographic-PSR volume computation method achieves high accuracy and reproducibility in vitro. The excellent in vitro correlation between 3D echocardiography-PSR and MRI indicates that MRI may also serve as an in vivo standard of comparison.

Publication types

  • Comparative Study

MeSH terms

  • Cardiac Volume*
  • Echocardiography* / instrumentation
  • Humans
  • Image Processing, Computer-Assisted*
  • Magnetic Resonance Imaging*
  • Models, Structural
  • Reproducibility of Results