Datamonkey: rapid detection of selective pressure on individual sites of codon alignments

Bioinformatics. 2005 May 15;21(10):2531-3. doi: 10.1093/bioinformatics/bti320. Epub 2005 Feb 15.


Datamonkey is a web interface to a suite of cutting edge maximum likelihood-based tools for identification of sites subject to positive or negative selection. The methods range from very fast data exploration to the some of the most complex models available in public domain software, and are implemented to run in parallel on a cluster of computers.

Availability: In the future, we plan to expand the collection of available analytic tools, and provide a package for installation on other systems.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms*
  • Base Sequence
  • Chromosome Mapping / methods*
  • Codon / genetics*
  • Evolution, Molecular*
  • Internet
  • Molecular Sequence Data
  • Selection, Genetic*
  • Sequence Alignment / methods*
  • Sequence Analysis, DNA / methods*
  • Software
  • User-Computer Interface


  • Codon