CREB gene transcription factors: role in molecular mechanisms of alcohol and drug addiction

Alcohol Clin Exp Res. 2005 Feb;29(2):176-84. doi: 10.1097/01.alc.0000153550.31168.1d.


This article presents the proceedings of a symposium presented at the meeting of the Research Society on Alcoholism, held in Vancouver, British Columbia, Canada, in June 2004. The organizers and chairpersons were Subhash C. Pandey and Fulton Crews. The presentations were (1) Ethanol Modulation of CREB: Role in Dependence and Withdrawal, by Fulton Crews; (2) Effects of D1 Dopamine Receptor Activation During Withdrawal From Chronic Morphine: Enhanced CREB Activation and Decreased Conditioned Place Aversion, by Elena H. Chartoff; (3) CREB-Haplodeficient Mice: Role in Anxiety and Alcohol-Drinking Behaviors, by Subhash C. Pandey; and (4) A Role for CREB in Stress and Drug Addiction, by Julie A. Blendy.

Publication types

  • Congress
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alcoholism / genetics*
  • Alcoholism / metabolism*
  • Animals
  • Cyclic AMP Response Element-Binding Protein / genetics*
  • Cyclic AMP Response Element-Binding Protein / physiology
  • Humans
  • Substance-Related Disorders / genetics
  • Substance-Related Disorders / metabolism


  • Cyclic AMP Response Element-Binding Protein