Candida Glabrata Endophthalmitis Treated Successfully With Caspofungin

Clin Infect Dis. 2005 Mar 1;40(5):e46-8. doi: 10.1086/427753. Epub 2005 Feb 1.

Abstract

A 39-year-old man with Candida glabrata endophthalmitis was successfully treated with a 28-day course of intravenous caspofungin. Presence of underlying renal insufficiency and infection with a drug-resistant strain precluded use of amphotericin B or fluconazole. Intravitreal administration of antifungals and vitrectomy were not required. The role of caspofungin in Candida endophthalmitis is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Candida glabrata / drug effects
  • Candida glabrata / isolation & purification*
  • Candidiasis / diagnosis*
  • Candidiasis / drug therapy
  • Candidiasis / microbiology
  • Caspofungin
  • Drug Resistance, Multiple, Fungal
  • Echinocandins
  • Endophthalmitis / drug therapy*
  • Endophthalmitis / microbiology*
  • Endophthalmitis / pathology
  • Humans
  • Lipopeptides
  • Male
  • Peptides, Cyclic / therapeutic use*

Substances

  • Antifungal Agents
  • Echinocandins
  • Lipopeptides
  • Peptides, Cyclic
  • Caspofungin