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, 6 (2), 119-27

The Genetic Theory of Adaptation: A Brief History


The Genetic Theory of Adaptation: A Brief History

H Allen Orr. Nat Rev Genet.


Theoretical studies of adaptation have exploded over the past decade. This work has been inspired by recent, surprising findings in the experimental study of adaptation. For example, morphological evolution sometimes involves a modest number of genetic changes, with some individual changes having a large effect on the phenotype or fitness. Here I survey the history of adaptation theory, focusing on the rise and fall of various views over the past century and the reasons for the slow development of a mature theory of adaptation. I also discuss the challenges that face contemporary theories of adaptation.

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