Abstract
Structure-function analysis of the Dishevelled (Dsh) protein in frog embryos has defined sequences that regulate Dsh nuclear localization, which proves critical for Wnt signaling.
MeSH terms
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Adaptor Proteins, Signal Transducing
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Animals
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Cell Nucleus / physiology
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Dishevelled Proteins
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Mutation / genetics
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Nuclear Envelope / physiology*
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Nuclear Export Signals / genetics
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Nuclear Export Signals / physiology
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Phosphoproteins / physiology*
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Protein Transport / physiology
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Signal Transduction / physiology*
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Wnt Proteins / genetics
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Wnt Proteins / physiology*
Substances
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Adaptor Proteins, Signal Transducing
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Dishevelled Proteins
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Nuclear Export Signals
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Phosphoproteins
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Wnt Proteins