Assessment of post-vaccination tuberculin sensitivity in Lagos-Nigeria

Eur J Epidemiol. 1992 Jan;8(1):128-31. doi: 10.1007/BF03334987.

Abstract

An increase in the number of cases of tuberculosis, especially in children, has been observed recently. Post-vaccination conversion rate in babies immunised with BCG was assessed. Sensitization was detected as early as 4 weeks after BCG inoculation. Although 84.2% had physical evidence of BCG inoculation only 69.8% had developed detectable sensitization to the tubercle bacilli as shown by the Mantoux test.

MeSH terms

  • BCG Vaccine / immunology*
  • Humans
  • Infant, Newborn
  • Nigeria / epidemiology
  • Random Allocation
  • Tuberculin / immunology*
  • Tuberculin Test
  • Tuberculosis / epidemiology
  • Tuberculosis / immunology*
  • Tuberculosis / prevention & control
  • Vaccination

Substances

  • BCG Vaccine
  • Tuberculin