The application of micro reactors for organic synthesis

Chem Soc Rev. 2005 Mar;34(3):235-46. doi: 10.1039/b313866f. Epub 2005 Feb 1.

Abstract

This tutorial review describes how micro reactors are being applied to synthetic chemistry covering a wide range of applications, from the preparation of nanograms of material for drug discovery and screening to the multi-tonne production of fine chemicals. This article explores how miniaturisation may revolutionise chemical synthesis and demonstrates that products are generated in higher yield and purity compared to the equivalent bulk reactions, in much shorter periods of time.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Combinatorial Chemistry Techniques*
  • Computer-Aided Design*
  • Dipeptides / chemical synthesis
  • Drug Design
  • Miniaturization
  • Molecular Structure
  • Organic Chemicals / chemical synthesis*
  • Pharmaceutical Preparations
  • Technology, Pharmaceutical / methods*

Substances

  • Dipeptides
  • Organic Chemicals
  • Pharmaceutical Preparations