Marine actinomycetes as a source of novel secondary metabolites

Antonie Van Leeuwenhoek. 2005 Jan;87(1):37-42. doi: 10.1007/s10482-004-6538-8.


A set of 600 actinomycetes strains which were isolated from marine sediments from various sites in the Pacific and Atlantic Oceans were screened for the production of bioactive secondary metabolites. Marine streptomycete strains were found to be producers of well known chemically diverse antibiotics isolated from terrestrial streptomycetes, as in the case of marine Micromonospora strains. New marine members of the rare genus Verrucosispora seem to be a promising source for novel bioactive secondary metabolites as shown in the case of the abyssomicin producing strain AB-18-032.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actinomycetales / classification
  • Actinomycetales / growth & development
  • Actinomycetales / isolation & purification*
  • Actinomycetales / metabolism*
  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / isolation & purification*
  • Atlantic Ocean
  • Culture Media / chemistry
  • Geologic Sediments / microbiology*
  • Micromonosporaceae / classification
  • Micromonosporaceae / growth & development
  • Micromonosporaceae / isolation & purification
  • Micromonosporaceae / metabolism
  • Molecular Structure
  • Pacific Ocean
  • Seawater


  • Anti-Bacterial Agents
  • Culture Media