Bilateral subthalamic nucleus stimulation improves health-related quality of life in Parkinsonian patients

Parkinsonism Relat Disord. 2005 Mar;11(2):89-94. doi: 10.1016/j.parkreldis.2004.08.006.


Parkinson's disease (PD) is a common neurological disorder. Recently, bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an option in the treatment of severe PD. We measured the health-related quality of life (HRQoL) of 27 parkinsonian patients, who underwent a bilateral STN-operation. The instruments used for the evaluation of the HRQoL were the Parkinson's Disease Questionnaire (PDQ-39) and the Finnish version of the Nottingham Health Profile (NHP). We found that the quality of life significantly improved when measured with both HRQoL scales. Clinical improvement and improvement in HRQoL were positively correlated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Deep Brain Stimulation / methods*
  • Female
  • Follow-Up Studies
  • Functional Laterality
  • Health Status
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / psychology*
  • Parkinson Disease / therapy*
  • Quality of Life*
  • Subthalamic Nucleus / physiology*
  • Surveys and Questionnaires