Aggressive HIV-1?

Retrovirology. 2005 Feb 28:2:13. doi: 10.1186/1742-4690-2-13.


New York City health officials announced on February 11, 2005 that a patient rapidly developed full-blown AIDS shortly after being diagnosed with a rare, drug-resistant strain of HIV-1. The New York City Department of Health issued an alert to all hospitals and doctors and a press conference was held to announce the emergence of an aggressive HIV-1 strain that may be difficult to treat and that appears to trigger rapid progression to AIDS. Is the panic justified?

MeSH terms

  • Acquired Immunodeficiency Syndrome / diagnosis*
  • Acquired Immunodeficiency Syndrome / drug therapy
  • Acquired Immunodeficiency Syndrome / physiopathology*
  • Adult
  • Anti-HIV Agents / pharmacology
  • Disease Progression
  • Drug Resistance, Multiple*
  • Drug Resistance, Viral*
  • HIV Protease Inhibitors / pharmacology
  • HIV-1 / drug effects*
  • HIV-1 / pathogenicity*
  • Humans
  • Male
  • New York City
  • Reverse Transcriptase Inhibitors / pharmacology
  • Time Factors


  • Anti-HIV Agents
  • HIV Protease Inhibitors
  • Reverse Transcriptase Inhibitors