Coley's toxins in perspective

Nature. 1992 May 7;357(6373):11-2. doi: 10.1038/357011a0.


Despite initial hopes, the efficacy of tumour necrosis factor in treating cancer patients has been disappointing. But a more careful selection of patients, and more appropriate treatment, might be fruitful.

Publication types

  • Biography
  • Historical Article
  • Portrait

MeSH terms

  • Bacterial Vaccines / history*
  • Bacterial Vaccines / therapeutic use
  • History, 19th Century
  • History, 20th Century
  • Humans
  • Sarcoma / therapy*
  • Soft Tissue Neoplasms / therapy*
  • Tumor Necrosis Factor-alpha / therapeutic use


  • Bacterial Vaccines
  • Tumor Necrosis Factor-alpha

Personal name as subject

  • W B Coley