Hand preference, immune system disorder and cognitive function among gay/bisexual men: the Multicenter AIDS Cohort Study (MACS)

Neuropsychologia. 1992 Mar;30(3):229-35. doi: 10.1016/0028-3932(92)90002-4.


This study evaluated the self-reported patterns of handedness among a large subsample (n = 1612) of the gay/bisexual men comprising the Multicenter AIDS Cohort Study (MACS). There was a small but significant elevation in left-handedness among gay/bisexual men compared to available normative data. However, there were no differences within the cohort in measures of immune function, self-reported autoimmune disorders, asthma, or hay fever, although there was an association between handedness and allergy. Performance on neuropsychological tests also did not differ as a function of handedness.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acquired Immunodeficiency Syndrome / physiopathology*
  • Acquired Immunodeficiency Syndrome / psychology
  • Adult
  • Autoimmune Diseases / physiopathology*
  • Autoimmune Diseases / psychology
  • Bisexuality* / psychology
  • Cohort Studies
  • Disease Susceptibility / physiopathology
  • Disease Susceptibility / psychology
  • Functional Laterality / physiology*
  • HIV Seropositivity / physiopathology
  • HIV Seropositivity / psychology
  • Homosexuality* / psychology
  • Humans
  • Hypersensitivity / physiopathology*
  • Hypersensitivity / psychology
  • Male
  • Neuropsychological Tests*
  • Risk Factors