Panax notoginseng supplementation enhances physical performance during endurance exercise

J Strength Cond Res. 2005 Feb;19(1):108-14. doi: 10.1519/00124278-200502000-00019.


The purpose of this study was to investigate whether a single 1,350-mg dose of Panax notoginseng (PNG) could enhance aerobic capacity, endurance, and mean blood pressure (MAP) in young adults. We randomly assigned 29 untrained adults, aged 20-35 years, to an experimental (EXP, n = 13) or a control (CON, n = 16) group. For 30 days, the EXP took 1,350 mg per day of PNG capsule and the CON consumed 1,350 mg per day of starch capsule. Measurement variables were taken before and after 30 days of either PNG supplement or placebo. Results show that the EXP improved (p < 0.05) their endurance time by >7 minutes, and lowered (p < 0.05) maximal MAP (from 113 +/- 12 to 109 +/- 14 mm Hg) and Vo2 at the 24th minute (from 32.5 +/- 8 to 27.6 +/- 8 during endurance cycle exercise. Based on this study, we conclude that 1,350 mg per day PNG supplement for 30 days improved endurance time to exhaustion, and lowered MAP and Vo2 during endurance exercise.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Pressure / drug effects
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Exercise Test*
  • Female
  • Humans
  • Male
  • Oxygen Consumption / drug effects
  • Panax*
  • Physical Endurance / drug effects*
  • Phytotherapy*