SRprises along a messenger's journey
- PMID: 15749011
- DOI: 10.1016/j.molcel.2005.02.020
SRprises along a messenger's journey
Abstract
SR (serine/arginine-rich) proteins were originally identified as essential splicing factors. Recent work, however, has implicated these proteins in numerous additional steps of mRNA metabolism, including nuclear export, RNA stability, mRNA quality control, and translation.
Similar articles
-
SR-related proteins and the processing of messenger RNA precursors.Biochem Cell Biol. 1999;77(4):277-91. Biochem Cell Biol. 1999. PMID: 10546891 Review.
-
[Phosphorylation of serine-arginine rich proteins--pleiotropic effect of one type posttranslational modification].Postepy Biochem. 2006;52(4):383-9. Postepy Biochem. 2006. PMID: 17536507 Review. Polish.
-
RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA.Nucleic Acids Res. 2006 Feb 25;34(4):1237-49. doi: 10.1093/nar/gkl007. Print 2006. Nucleic Acids Res. 2006. PMID: 16500893 Free PMC article.
-
Quality control of messenger ribonucleoprotein particles in the nucleus and at the pore.Curr Opin Cell Biol. 2005 Jun;17(3):294-301. doi: 10.1016/j.ceb.2005.04.007. Curr Opin Cell Biol. 2005. PMID: 15901500 Review.
-
An interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA processing/export and mRNA stability.Mol Cell Biol. 2007 Sep;27(18):6569-79. doi: 10.1128/MCB.00881-07. Epub 2007 Jul 16. Mol Cell Biol. 2007. PMID: 17636033 Free PMC article.
Cited by
-
Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2802-11. doi: 10.1073/pnas.1303445110. Epub 2013 Jul 8. Proc Natl Acad Sci U S A. 2013. PMID: 23836656 Free PMC article.
-
NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.Elife. 2013 Jan 22;2:e00178. doi: 10.7554/eLife.00178. Elife. 2013. PMID: 23359859 Free PMC article.
-
A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).Genes Dev. 2010 Jun 1;24(11):1073-4. doi: 10.1101/gad.1934910. Genes Dev. 2010. PMID: 20516191 Free PMC article. No abstract available.
-
The hnRNP C tetramer binds to CBC on mRNA and impedes PHAX recruitment for the classification of RNA polymerase II transcripts.Nucleic Acids Res. 2023 Feb 22;51(3):1393-1408. doi: 10.1093/nar/gkac1250. Nucleic Acids Res. 2023. PMID: 36620872 Free PMC article.
-
Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins.Mol Biol Cell. 2008 Jan;19(1):327-38. doi: 10.1091/mbc.e07-03-0255. Epub 2007 Oct 31. Mol Biol Cell. 2008. PMID: 17978099 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
