SRprises Along a Messenger's Journey

Mol Cell. 2005 Mar 4;17(5):613-5. doi: 10.1016/j.molcel.2005.02.020.

Abstract

SR (serine/arginine-rich) proteins were originally identified as essential splicing factors. Recent work, however, has implicated these proteins in numerous additional steps of mRNA metabolism, including nuclear export, RNA stability, mRNA quality control, and translation.

Publication types

  • Review

MeSH terms

  • Animals
  • Arginine / chemistry*
  • Humans
  • Models, Biological
  • Nucleocytoplasmic Transport Proteins / physiology*
  • Phosphorylation
  • Protein Biosynthesis*
  • Protein Structure, Tertiary
  • RNA Precursors
  • RNA Splicing
  • RNA Transport
  • RNA, Messenger / metabolism
  • Serine / chemistry*

Substances

  • Nucleocytoplasmic Transport Proteins
  • RNA Precursors
  • RNA, Messenger
  • Serine
  • Arginine