PSIbase: a database of Protein Structural Interactome map (PSIMAP)

Bioinformatics. 2005 May 15;21(10):2541-3. doi: 10.1093/bioinformatics/bti366. Epub 2005 Mar 3.


Protein Structural Interactome map (PSIMAP) is a global interaction map that describes domain-domain and protein-protein interaction information for known Protein Data Bank structures. It calculates the Euclidean distance to determine interactions between possible pairs of structural domains in proteins. PSIbase is a database and file server for protein structural interaction information calculated by the PSIMAP algorithm. PSIbase also provides an easy-to-use protein domain assignment module, interaction navigation and visual tools. Users can retrieve possible interaction partners of their proteins of interests if a significant homology assignment is made with their query sequences.

Availability: and

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Computer Graphics
  • Computer Simulation
  • Databases, Protein*
  • Internet
  • Models, Biological
  • Models, Chemical
  • Models, Molecular
  • Protein Binding
  • Protein Conformation
  • Protein Interaction Mapping / methods*
  • Proteins / analysis
  • Proteins / chemistry*
  • Proteins / metabolism*
  • Sequence Alignment / methods*
  • Sequence Analysis, Protein / methods*
  • Sequence Homology, Amino Acid
  • User-Computer Interface*


  • Proteins