In vitro host-cell susceptibility to Usutu virus

Emerg Infect Dis. 2005 Feb;11(2):298-301. doi: 10.3201/eid1102.041016.

Abstract

We investigated the susceptibility to Usutu virus (Flavivirus) of 13 permanent cell lines, 3 primary cell cultures, and chicken embryos. Vero, PK-15, and goose embryo fibroblast cells developed cytopathic effects; however, viral multiplication was detected in all mammalian cell types by immunohistochemical tests. Chicken embryo fibroblast cells and chicken embryos were resistant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line / virology*
  • Cells, Cultured
  • Chick Embryo / virology*
  • Chlorocebus aethiops
  • Cytopathogenic Effect, Viral / physiology
  • Fibroblasts / virology
  • Flavivirus / growth & development*
  • Flavivirus / pathogenicity
  • Flavivirus Infections / virology*
  • HeLa Cells
  • Humans
  • Immunohistochemistry
  • Vero Cells