Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka

Lancet. 2005 Mar 5-11;365(9462):876-8. doi: 10.1016/S0140-6736(05)71046-1.

Abstract

A man injured in the tsunami of Dec 26, 2004, returned to Sydney for management of his soft-tissue injuries. Despite broad-spectrum antibiotics, surgical wound debridement, and vigilant wound care, his condition worsened. Muscle and fat necrosis developed in a previously debrided thigh wound, and necrotising lesions arose from previous abrasions. Histological analysis showed mucormycosis in three non-contiguous sites, and Apophysomyces elegans was isolated from excised wound tissue. Wound infections, both bacterial and fungal, will undoubtedly add to the morbidity and mortality already recorded in tsunami-affected areas. Other cases [correction] of cutaneous mucormycosis might develop in survivors, but this disease can be difficult to diagnose and even harder to treat, particularly in those remaining in affected regions.

Publication types

  • Case Reports

MeSH terms

  • Dermatomycoses / diagnosis
  • Dermatomycoses / drug therapy
  • Dermatomycoses / microbiology*
  • Disasters*
  • Fasciitis, Necrotizing / diagnosis
  • Fasciitis, Necrotizing / microbiology*
  • Fasciitis, Necrotizing / therapy
  • Humans
  • Male
  • Middle Aged
  • Mucormycosis / diagnosis*
  • Mucormycosis / drug therapy
  • Mucormycosis / etiology
  • Soft Tissue Infections / drug therapy
  • Soft Tissue Infections / microbiology
  • Soft Tissue Injuries / microbiology*
  • Sri Lanka
  • Wound Infection / microbiology*