Abstract
It has been proposed that the aggregation of nascent transmembrane segments of polytopic proteins is prevented by chaperones present in the endoplasmic reticulum membrane; now the first experimental support for this proposal has been reported.
MeSH terms
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Carrier Proteins / metabolism
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Endoplasmic Reticulum / metabolism*
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Membrane Proteins / biosynthesis
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Membrane Proteins / metabolism*
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Models, Biological*
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Molecular Chaperones / metabolism*
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Protein Folding
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Protein Structure, Tertiary / physiology
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SEC Translocation Channels
Substances
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Carrier Proteins
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Membrane Proteins
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Molecular Chaperones
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SEC Translocation Channels