High-frequency oscillatory ventilation: lessons from the neonatal/pediatric experience

Crit Care Med. 2005 Mar;33(3 Suppl):S115-21. doi: 10.1097/01.ccm.0000155923.97849.6d.


Efforts to minimize ventilator-induced lung injury in adults with hypoxemic respiratory failure have recently focused on the potential role of high-frequency oscillatory ventilation (HFOV). However, HFOV has been studied in newborns with hypoxemic respiratory failure for nearly 3 decades. In this brief review, we attempt to summarize key physiological principles learned from this cumulative neonatal/pediatric experience with HFOV.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Child
  • Child, Preschool
  • High-Frequency Ventilation*
  • Humans
  • Infant
  • Infant, Newborn
  • Lung / physiology
  • Respiratory Distress Syndrome