Skew-Laplace distribution in Gram-negative bacterial axenic cultures: new insights into intrinsic cellular heterogeneity

Microbiology (Reading). 2005 Mar;151(Pt 3):749-755. doi: 10.1099/mic.0.27460-0.

Abstract

The application of flow cytometry and skew-Laplace statistical analysis to assess cellular heterogeneity in Gram-negative axenic cultures is reported. In particular, fit to the log-skew-Laplace distribution for cellular side scatter or 'granulosity' is reported, and a number of theoretical and applied issues are considered in relation to the biological significance of this fit.

MeSH terms

  • Culture Media
  • Data Interpretation, Statistical
  • Flow Cytometry / statistics & numerical data
  • Gram-Negative Bacteria / cytology
  • Gram-Negative Bacteria / growth & development*
  • Gram-Negative Bacteria / metabolism
  • Likelihood Functions
  • Models, Theoretical

Substances

  • Culture Media