Re-analysis of Data and Its Integration

FEBS Lett. 2005 Mar 21;579(8):1802-7. doi: 10.1016/j.febslet.2005.02.006.

Abstract

To understand a biological process it is clear that a single approach will not be sufficient, just like a single measurement on a protein--such as its expression level--does not describe protein function. Using reference sets of proteins as benchmarks different approaches can be scaled and integrated. Here, we demonstrate the power of data re-analysis and integration by applying it in a case study to data from deletion phenotype screens and mRNA expression profiling.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Computational Biology*
  • Databases, Genetic
  • Gene Expression Profiling
  • Models, Biological
  • Phenotype
  • Proteins / genetics*
  • Proteins / physiology
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / physiology

Substances

  • Proteins