Screening for chronic hepatitis C: American College of Preventive Medicine practice policy statement

Am J Prev Med. 2005 Apr;28(3):327-30. doi: 10.1016/j.amepre.2004.12.009.


Hepatitis C is an under-diagnosed and prevalent bloodborne illness, resulting in chronic cirrhosis in up to 25% of those infected. While the overall prevalence in the United States is 1.7%, high-risk populations may have up to 80% prevalence. The mechanism of transmission is well understood, but effective preventive measures are hampered by economic, social, and political factors. Antiviral treatment is expensive, and efficacy ranges from 40% to 85%. The value of screening high-risk populations has been demonstrated, and should be expanded; however, there is insufficient evidence to recommend universal screening for adults.

Publication types

  • Review

MeSH terms

  • Attitude of Health Personnel
  • Female
  • Hepatitis C* / diagnosis
  • Hepatitis C* / etiology
  • Hepatitis C* / prevention & control
  • Humans
  • Male
  • Population Surveillance / methods*
  • Prevalence
  • Public Policy
  • Societies, Medical*
  • United States / epidemiology