Studies on constituents of fruit body of Polyporus umbellatus and their cytotoxic activity

Chem Pharm Bull (Tokyo). 1992 Jan;40(1):143-7. doi: 10.1248/cpb.40.143.


From the crude drug Chorei, the fruit body of Polyporus umbellatus, seven new components named polyporusterone A, B, C, D, E, F and G, were isolated and their structures were determined on the basis of the spectral data. These compounds showed cytotoxic action on leukemia 1210 cell proliferation.

MeSH terms

  • Animals
  • Antineoplastic Agents / isolation & purification*
  • Leukemia L1210 / drug therapy
  • Magnetic Resonance Spectroscopy
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Polyporaceae / metabolism*


  • Antineoplastic Agents
  • Plant Extracts