How does the kidney filter plasma?

Physiology (Bethesda). 2005 Apr;20:96-101. doi: 10.1152/physiol.00045.2004.


The kidneys filter the plasma in special filtration units-glomeruli-and thereby excrete low-molecular-weight waste products into the urine. The mechanisms of glomerular filtration have been a matter of controversy for several decades, but recent data have revealed new details about the molecular nature of the filter and have demonstrated a central role for the podocyte slit diaphragm in the filtration process.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Kidney Glomerulus / cytology*
  • Kidney Glomerulus / physiology*
  • Plasma
  • Proteinuria / physiopathology*
  • Ultrafiltration*