High-intensity focused ultrasound in the treatment of solid tumours

Nat Rev Cancer. 2005 Apr;5(4):321-7. doi: 10.1038/nrc1591.


Traditionally, surgery has been the only cure for many solid tumours. Technological advances have catalysed a shift from open surgery towards less invasive techniques. Laparoscopic surgery and minimally invasive techniques continue to evolve, but for decades high-intensity focused ultrasound has promised to deliver the ultimate objective - truly non-invasive tumour ablation. Only now, however, with recent improvements in imaging, has this objective finally emerged as a real clinical possibility.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Catheter Ablation
  • Humans
  • Laparoscopy
  • Neoplasm Metastasis
  • Neoplasms / therapy*
  • Ultrasonic Therapy* / adverse effects
  • Ultrasonic Therapy* / methods