Acute peripheral facial palsy in adults

J Neurol. 2005 Jun;252(6):672-6. doi: 10.1007/s00415-005-0715-1. Epub 2005 Mar 23.


Objective: To collect epidemiological data of peripheral facial palsy, and especially to chart the incidence and clinical characteristics of Lyme associated facial palsy.

Material and methods: We included consecutive adult patients presenting with peripheral facial palsy in Vest-Agder County from January 1997 to December 1998. The facial palsy was graded according to the House and Brackman facial function scoring system,and cerebrospinal fluid and serum samples were examined for Borrelia burgdorferi antibodies and virus antibodies. Final outcome was evaluated by follow up visits or telephone interview.

Results: Sixty nine patients were included and followed until complete recovery, or for 5 years. Ten per cent were caused by Lyme disease, 17% by virus infection, 4% by other causes and 68% were classified as Bell's palsy. All patients with Lyme facial palsy had additional neurological symptoms, and 87% reported constitutional complaints. The overall final outcome was good with complete recovery in 77%, slight sequelae in 20% and moderate sequelae in 3%. No patients experienced severe sequelae. Two of 28 patients examined with neurography had absent compound muscle action potentials in orbicularis oculi. Both made good recovery with only slight sequelae.

Conclusions: Peripheral facial palsy is a common disorder with a favourable prognosis. Lyme disease seems to be an infrequent cause of facial palsy in patients without constitutional symptoms or additional neurological findings.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Antibodies / metabolism
  • Borrelia burgdorferi / immunology
  • Enzyme-Linked Immunosorbent Assay / methods
  • Facial Paralysis / diagnosis*
  • Facial Paralysis / epidemiology*
  • Facial Paralysis / etiology
  • Facial Paralysis / metabolism
  • Female
  • Humans
  • Lyme Disease / complications
  • Lyme Disease / diagnosis*
  • Lyme Disease / epidemiology*
  • Lyme Disease / metabolism
  • Male
  • Middle Aged
  • Retrospective Studies
  • Seasons


  • Antibodies