Clinician-parent communication during informed consent for pediatric leukemia trials

J Pediatr Psychol. Apr-May 2005;30(3):219-29. doi: 10.1093/jpepsy/jsi032. Epub 2005 Feb 23.


Objective: To address the need to describe informed consent in pediatric settings and to identify barriers to parent understanding, this study assessed how aspects of clinician-parent communication during the informed consent conference (ICC) relate to parent understanding of informed consent and parent perception of the impact of the ICC on their anxiety and control.

Methods: Parents of 127 children with newly diagnosed leukemia who were eligible for clinical trials were the participants. The study used comprehensive methods including both observational and self-report assessment methods.

Results: Structural equation modeling demonstrated that parent race and socioeconomic status (SES) were powerful predictors of clinician-parent communication, parent anxiety and control as a result of the ICC, and parent understanding. Clinician information giving and partnership building predicted parent participation during the ICC.

Conclusions: These findings may be used to design interventions that increase the effectiveness of the ICC by identifying specific elements of the conference that influence parent affect and understanding.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Anxiety / prevention & control
  • Anxiety / psychology
  • Child
  • Child, Preschool
  • Clinical Trials as Topic
  • Communication*
  • Decision Making
  • Female
  • Humans
  • Infant
  • Informed Consent*
  • Leukemia / therapy*
  • Male
  • Parents / psychology*
  • Professional-Family Relations*