Prevalence and genotypes of hepatitis G virus among hemodialysis patients in Eastern Anatolia, Turkey

Med Princ Pract. 2005 Mar-Apr;14(2):102-6. doi: 10.1159/000083920.

Abstract

Objectives: To study the prevalence and genotype distribution of hepatitis G virus (HGV) in hemodialysis patients in East Anatolia, Turkey.

Subjects and materials: Eighty-nine hemodialysis patients and 30 healthy individuals were analyzed by using reverse-transcriptase nested polymerase chain reaction with primers specific for 5' untranslated region. HGV genotyping was performed by PCR and three randomly selected HGV-positive samples were sequenced.

Results: Of the 89 hemodialysis patients, HGV RNA was detected in 9 (10.2%). All of our isolates were assigned to genotype 2.

Conclusion: Our results showed that hemodialysis patients carry the risk for HGV infection in East Anatolia, Turkey.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Base Sequence
  • DNA Primers
  • Female
  • GB virus C / classification*
  • GB virus C / genetics*
  • GB virus C / isolation & purification
  • Genotype*
  • Humans
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • RNA, Viral / blood
  • Renal Dialysis*
  • Seroepidemiologic Studies
  • Turkey

Substances

  • DNA Primers
  • RNA, Viral