[Mortality and morbidity of low-birth-weight infants. Current prognosis and future perspectives]

Bull Acad Natl Med. 2004;188(7):1127-39; discussion 1139-41.
[Article in French]


In a retrospective epidemiologic study conducted from January 1996 to December 2002, 2555 low-birth-weight infants (less than 2500 g) were admitted to the neonatal intensive care unit of E Herriot Hospital in Lyon, France. Very low birth weight (795 infants) was defined as a birth weight below 1500 g. The total mortality rate among these latter infants was 8%. The mortality rate was less than 25% among infants with a gestational age of at least 25 weeks. Neonatal morbidity mainly consisted of respiratory distress syndrome and cerebral hemorrhage. Sequelae at age 2 years (corrected) affected less than 10% of surviving in very-low-birth-weight infants. Gestational age is thus an important predictor of survival and functional outcome in very-low-birth-weight infants.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Cerebral Hemorrhage / epidemiology
  • Follow-Up Studies
  • France / epidemiology
  • Gestational Age
  • Humans
  • Infant Mortality* / trends
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Infant, Premature, Diseases / epidemiology*
  • Infant, Premature, Diseases / mortality
  • Infant, Very Low Birth Weight
  • Intensive Care Units, Neonatal
  • Prognosis
  • Respiratory Distress Syndrome, Newborn / epidemiology
  • Retrospective Studies
  • Time Factors