Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones

Radovan Sebesta; Maria Gabriella Pizzuti; Arnold J Boersma; Adriaan J Minnaard; Ben L Feringa

doi:10.1039/b417727d

Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones

Chem Commun (Camb). 2005 Apr 7:(13):1711-3. doi: 10.1039/b417727d. Epub 2005 Feb 2.

Authors

Radovan Sebesta¹, Maria Gabriella Pizzuti, Arnold J Boersma, Adriaan J Minnaard, Ben L Feringa

Affiliation

¹ Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747, AG Groningen, The Netherlands.

PMID: 15791307
DOI: 10.1039/b417727d

Abstract

The first, highly enantioselective, copper/phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents to N-substituted 2,3-dehydro-4-piperidones is described.