Current perspectives on the management of gastroparesis

J Postgrad Med. Jan-Mar 2005;51(1):54-60.

Abstract

Gastroparesis is a condition of abnormal gastric motility characterised by delayed gastric emptying in the absence of mechanical outlet obstruction. It is seen commonly in people with diabetes but is idiopathic in a third of patients. Symptoms include nausea and vomiting, post-prandial fullness and early satiety, and abdominal bloating and discomfort. Investigations fall into three categories: gastric emptying studies, intraluminal pressure measurements and recording of gastric myoelectrical activity. Nuclear scintigraphy is considered the gold standard for diagnosing and quantifying delayed gastric emptying. Treatment options include diet and behavioural changes, prokinetic drugs and surgical interventions. New advances in drug therapy and gastric electrical stimulation techniques hold considerable promise.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Diet
  • Gastrointestinal Agents / therapeutic use
  • Gastroparesis / diagnosis
  • Gastroparesis / physiopathology
  • Gastroparesis / therapy*
  • Humans

Substances

  • Anti-Bacterial Agents
  • Gastrointestinal Agents