Efficacy of the KTP laser in the treatment of middle ear cholesteatoma

Otol Neurotol. 2005 Mar;26(2):135-9. doi: 10.1097/00129492-200503000-00001.


Objective: To evaluate whether ancillary use of the KTP (potassium titanyl phosphate) laser can diminish the rate of residual disease in intact canal wall cholesteatoma surgery.

Study design: Prospective controlled parallel group study.

Setting: Two neighboring district general hospitals, one with a KTP laser and one without.

Patients: All patients undergoing staged intact canal wall surgery for cholesteatoma.

Intervention: Staged intact canal wall surgery for cholesteatoma.

Main outcome measure: Presence or absence of residual disease at the second stage operation, performed at least 12 months after the first operation.

Results: Thirty-three patients underwent treatment without and 36 underwent treatment with the laser. Ten patients without laser treatment had residual disease, whereas one patient had residual disease after laser treatment (p = 0.003). After adjustment using logistic regression, treatment still has a significant effect on outcome (p = 0.013). The number needed to treat is four.

Discussion: Ancillary use of the KTP laser in cholesteatoma surgery is a treatment that significantly improves complete removal of disease.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Child
  • Cholesteatoma, Middle Ear / surgery*
  • Ear Canal / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Laser Therapy*
  • Male
  • Middle Aged
  • Postoperative Complications / etiology
  • Postoperative Complications / surgery
  • Prospective Studies
  • Recurrence
  • Reoperation
  • Risk Factors