Molecular genetic approaches to developing quality protein maize

Trends Genet. 2005 Apr;21(4):227-33. doi: 10.1016/j.tig.2005.02.009.


Since its development more than two decades ago, Quality Protein Maize (QPM) has been adopted for cultivation in many regions of the developing world. Given the potential benefits of widespread use of QPM, research to better understand the genetic and biochemical mechanisms responsible for its altered kernel texture and protein quality is important. Recent investigations into the improved protein quality of the opaque2 mutant and the genetic mechanisms that can suppress its starchy kernel phenotype provide new insights to support the continued improvement of QPM. Chief among these developments are the use of transgenic approaches to improve nutritional quality and the discovery that an important component of modified endosperm texture in QPM is related to altered starch granule structure.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Chromosomes, Plant / genetics*
  • DNA-Binding Proteins / genetics*
  • Mutation / genetics
  • Plant Proteins / genetics*
  • Plants, Genetically Modified / genetics*
  • Starch / chemistry
  • Starch / genetics
  • Transcription Factors / genetics*
  • Zea mays / genetics*


  • DNA-Binding Proteins
  • Plant Proteins
  • Transcription Factors
  • opaque-2 protein, Zea mays
  • Starch