Review
doi: 10.1016/j.semcdb.2004.12.004.
Epub 2005 Jan 16.
Programmed cell death in the embryonic vertebrate limb
Affiliations
- PMID: 15797836
- DOI: 10.1016/j.semcdb.2004.12.004
Item in Clipboard
Review
Programmed cell death in the embryonic vertebrate limb
Semin Cell Dev Biol.
2005 Apr.
Abstract
The developing limb bud provides one of the best examples in which programmed cell death exerts major morphogenetic functions. In this work, we revise the distribution and the developmental significance of cell death in the embryonic vertebrate limb and its control by the BMP signalling pathway. In addition, paying special attention to the interdigital apoptotic zones, we review current data concerning the intracellular death machinery implicated in mesodermal limb apoptosis.
Similar articles
-
A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways.Dev Biol. 2004 Aug 1;272(1):39-52. doi: 10.1016/j.ydbio.2004.04.015. Dev Biol. 2004. PMID: 15242789
-
BMP-2/-4 mediate programmed cell death in chicken limb buds.Development. 1996 Dec;122(12):3725-34. doi: 10.1242/dev.122.12.3725. Development. 1996. PMID: 9012494
-
Control of skeletogenesis and programmed cell death in the developing avian limb bud by growth factors.Int J Dev Biol. 1996;Suppl 1:189S. Int J Dev Biol. 1996. PMID: 9087755 No abstract available.
-
Programmed cell death in the developing limb.Int J Dev Biol. 2002;46(7):871-6. Int J Dev Biol. 2002. PMID: 12455623 Review.
-
Interplay between the molecular signals that control vertebrate limb development.Int J Dev Biol. 2002;46(7):877-81. Int J Dev Biol. 2002. PMID: 12455624 Review.
Cited by
-
Expression of cyclin D1, cyclin D2, and N-myc in embryos of the direct developing frog Eleutherodactylus coqui, with a focus on limbs.Gene Expr Patterns. 2013 Jun-Jul;13(5-6):142-9. doi: 10.1016/j.gep.2013.02.005. Epub 2013 Mar 7. Gene Expr Patterns. 2013. PMID: 23473789 Free PMC article.
-
Fork head controls the timing and tissue selectivity of steroid-induced developmental cell death.J Cell Biol. 2007 Mar 12;176(6):843-52. doi: 10.1083/jcb.200611155. Epub 2007 Mar 5. J Cell Biol. 2007. PMID: 17339378 Free PMC article.
-
Patterning and post-patterning modes of evolutionary digit loss in mammals.Nature. 2014 Jul 3;511(7507):41-5. doi: 10.1038/nature13496. Epub 2014 Jun 18. Nature. 2014. PMID: 24990742 Free PMC article.
-
Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome.Am J Hum Genet. 2010 Aug 13;87(2):265-73. doi: 10.1016/j.ajhg.2010.07.003. Am J Hum Genet. 2010. PMID: 20691405 Free PMC article.
-
Dynamic changes after murine digit amputation: the MRL mouse digit shows waves of tissue remodeling, growth, and apoptosis.Wound Repair Regen. 2009 May-Jun;17(3):447-55. doi: 10.1111/j.1524-475X.2009.00492.x. Wound Repair Regen. 2009. PMID: 19660054 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
