Food fight: the NPY-serotonin link between aggression and feeding behavior

Sci STKE. 2005 Mar 29;2005(277):pe12. doi: 10.1126/stke.2772005pe12.

Abstract

Aggressive behavior in mammals is linked to feeding. Interactions between neuropeptide tyrosine (NPY) and serotonergic neurons provide this link. Studies of aggressive behavior in mice in which the Y(1) subtype of NPY receptor was knocked out further define the synaptic circuits responsible for the interrelation of these instinctive behaviors.

Publication types

  • Review

MeSH terms

  • Aggression / physiology*
  • Animals
  • Brain Mapping
  • Eating / physiology*
  • Feeding Behavior / physiology
  • Humans
  • Mice
  • Mice, Knockout
  • Neuropeptide Y / physiology*
  • Receptors, Neuropeptide Y / physiology*
  • Serotonin / physiology
  • Territoriality

Substances

  • Neuropeptide Y
  • Receptors, Neuropeptide Y
  • neuropeptide Y-Y1 receptor
  • Serotonin