The Monte Carlo SRNA-VOX code for 3D proton dose distribution in voxelized geometry using CT data

Phys Med Biol. 2005 Mar 7;50(5):1011-7. doi: 10.1088/0031-9155/50/5/023. Epub 2005 Feb 17.

Abstract

This paper describes the application of the SRNA Monte Carlo package for proton transport simulations in complex geometry and different material compositions. The SRNA package was developed for 3D dose distribution calculation in proton therapy and dosimetry and it was based on the theory of multiple scattering. The decay of proton induced compound nuclei was simulated by the Russian MSDM model and our own using ICRU 63 data. The developed package consists of two codes: the SRNA-2KG, which simulates proton transport in combinatorial geometry and the SRNA-VOX, which uses the voxelized geometry using the CT data and conversion of the Hounsfield's data to tissue elemental composition. Transition probabilities for both codes are prepared by the SRNADAT code. The simulation of the proton beam characterization by multi-layer Faraday cup, spatial distribution of positron emitters obtained by the SRNA-2KG code and intercomparison of computational codes in radiation dosimetry, indicate immediate application of the Monte Carlo techniques in clinical practice. In this paper, we briefly present the physical model implemented in the SRNA package, the ISTAR proton dose planning software, as well as the results of the numerical experiments with proton beams to obtain 3D dose distribution in the eye and breast tumour.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Breast / radiation effects
  • Breast Neoplasms / radiotherapy
  • Electrons
  • Eye / radiation effects
  • Eye Neoplasms / radiotherapy
  • Humans
  • Models, Theoretical
  • Monte Carlo Method
  • Normal Distribution
  • Phantoms, Imaging
  • Protons*
  • Radiographic Image Enhancement
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiometry
  • Radiotherapy Planning, Computer-Assisted / methods*
  • Radiotherapy, Conformal
  • Scattering, Radiation
  • Software
  • Time Factors
  • Tomography, X-Ray Computed / methods*

Substances

  • Protons