Over the past 10 years, growth of the Latino population in the United States has been most rapid in North Carolina. Project Realidad Latina (Latino Reality) was a qualitative exploratory study conducted to gain insight into the immigration experiences of 10 newly-arrived Latino adolescents living in rural North Carolina (NC). The study followed a community-based participatory research (CBPR) approach and used the photovoice method. Over a one-year period, adolescents partnered with public health practitioners and researchers in: generating photo-assignments, taking photographs based on these assignments, using the photographs for photo-discussions, and defining themes based on these photo-discussions. A photograph exhibition and community forum raised awareness among local decision-makers and community members of the issues and assets of Latino adolescents and initiated a process toward change. From the participants' words and photographs emerged contextual descriptions of issues that both challenged and facilitated their adaptation and quality of life in their school and community. Likewise, implications from the findings and the nature of the CBPR approach for future Latino adolescent health intervention research are presented.