Supervised learning through neuronal response modulation

Neural Comput. 2005 Mar;17(3):609-31. doi: 10.1162/0899766053019980.


Neural networks that are trained to perform specific tasks must be developed through a supervised learning procedure. This normally takes the form of direct supervision of synaptic plasticity. We explore the idea that supervision takes place instead through the modulation of neuronal excitability. Such supervision can be done using conventional synaptic feedback pathways rather than requiring the hypothetical actions of unknown modulatory agents. During task learning, supervised response modulation guides Hebbian synaptic plasticity indirectly by establishing appropriate patterns of correlated network activity. This results in robust learning of function approximation tasks evenwhenmultiple output units representing different functions share large amounts of common input. Reward-based supervision is also studied, and a number of potential advantages of neuronal response modulation are identified.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Feedback
  • Humans
  • Learning / physiology*
  • Models, Neurological*
  • Nerve Net / physiology*
  • Neural Networks, Computer*
  • Neuronal Plasticity / physiology
  • Neurons / physiology*
  • Probability
  • Reward
  • Synapses / physiology