Lepromatous iridocyclitis

Ocul Immunol Inflamm. 2005 Feb;13(1):95-9. doi: 10.1080/09273940490912380.

Abstract

A 36-year-old woman with no prior medical history presented with a unilateral decrease in vision and iridocyclitis to our hospital. External examination demonstrated multifocal, firm, elevated, non-tender skin nodules on the patient's face and left hand. In addition, slit-lamp biomicroscopy revealed gray, cheesy-appearing nodules on the iris surface of the affected eye. Anterior chamber paracentesis and pars plana vitrectomy did not reveal further information. Skin nodule biopsy, however, demonstrated multiple fragmented organisms within histiocytes, consistent with leprosy. The iridocyclitis resolved after treatment with dapsone, corticosteroids, and rifampin and her vision returned to 20/20.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aqueous Humor / microbiology
  • Dapsone / therapeutic use
  • Drug Therapy, Combination
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology*
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Iridocyclitis / diagnosis
  • Iridocyclitis / drug therapy
  • Iridocyclitis / microbiology*
  • Leprostatic Agents / therapeutic use
  • Leprosy, Lepromatous / diagnosis
  • Leprosy, Lepromatous / drug therapy
  • Leprosy, Lepromatous / microbiology*
  • Mycobacterium leprae / isolation & purification*
  • Prednisone / therapeutic use
  • Rifampin / therapeutic use
  • Skin / microbiology
  • Vitreous Body / microbiology

Substances

  • Glucocorticoids
  • Leprostatic Agents
  • Dapsone
  • Prednisone
  • Rifampin