Abstract
In Escherichia coli, the Rep helicase has been implicated in replication fork progression, replication restart, homologous recombination, and DNA repair. We show that a Neisseria gonorrhoeae rep mutant is deficient in the homologous-recombination-mediated processes of DNA transformation and pilus-based colony variation but not in DNA repair.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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DNA Damage / genetics
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DNA Helicases / physiology*
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DNA-Binding Proteins / genetics
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Molecular Sequence Data
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Neisseria gonorrhoeae / genetics*
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Recombination, Genetic*
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Transformation, Bacterial
Substances
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DNA-Binding Proteins
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DNA Helicases