Recent progress towards the application of hyperthermophiles and their enzymes

Curr Opin Chem Biol. 2005 Apr;9(2):166-73. doi: 10.1016/j.cbpa.2005.02.013.


The discovery of extremophiles has drastically changed our understanding towards the diversity of life itself and the conditions under which it can be sustained. Extremophiles have evolved to withstand and multiply under the extremes of temperature, pressure, pH and salinity. Hyperthermophiles are the group that have adapted to high temperature; many have been found to grow at temperatures above the boiling point of water. This review focuses on recent advances in application-based research on hyperthermophiles and their thermostable enzymes.

MeSH terms

  • Archaea / enzymology*
  • Archaea / genetics
  • Archaea / growth & development
  • Bacteria / enzymology*
  • Bacteria / genetics
  • Bacteria / growth & development
  • Biotechnology / methods*
  • Enzyme Stability
  • Enzymes / metabolism*
  • Genome, Archaeal
  • Genome, Bacterial
  • Hot Temperature


  • Enzymes