Paracrine Action Accounts for Marked Protection of Ischemic Heart by Akt-modified Mesenchymal Stem Cells

Nat Med. 2005 Apr;11(4):367-8. doi: 10.1038/nm0405-367.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Apoptosis
  • Bone Marrow Transplantation
  • Cell Hypoxia
  • Cells, Cultured
  • Culture Media, Conditioned
  • Green Fluorescent Proteins / pharmacology
  • Intercellular Signaling Peptides and Proteins / metabolism*
  • Mesenchymal Stem Cell Transplantation*
  • Mesenchymal Stem Cells / metabolism*
  • Myocardial Infarction / drug therapy
  • Myocardium / cytology*
  • Protein-Serine-Threonine Kinases / genetics*
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins c-akt
  • Rats

Substances

  • Culture Media, Conditioned
  • Intercellular Signaling Peptides and Proteins
  • Proto-Oncogene Proteins
  • Green Fluorescent Proteins
  • Akt1 protein, rat
  • Protein-Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-akt