Change in atherosclerosis progression in HIV-infected patients: ANRS Aquitaine Cohort, 1999-2004

AIDS. 2005 Apr 29;19(7):729-31. doi: 10.1097/01.aids.0000166097.46940.35.

Abstract

This study reported the changes in carotid intima-media thickness (IMT) during a 36-month period in 233 HIV-infected patients. Median IMT increased in the first 12 months and then decreased by month 36. The prevalence of treatment with lipid-lowering agents and protease inhibitor-free highly active antiretroviral therapy regimens increased, whereas smoking prevalence decreased. The progression of atherosclerosis in HIV-infected patients can be controlled. The impact of individual measures to reduce the cardiovascular risk should be evaluated further.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antiretroviral Therapy, Highly Active
  • Arteriosclerosis / pathology
  • Arteriosclerosis / therapy
  • Arteriosclerosis / virology*
  • Carotid Artery Diseases / pathology
  • Carotid Artery Diseases / virology
  • Carotid Artery, Common
  • Cholesterol, HDL / blood
  • Disease Progression
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • France
  • HIV Infections / complications*
  • HIV Infections / pathology
  • HIV Infections / therapy
  • HIV-1*
  • Humans
  • Hypolipidemic Agents / therapeutic use
  • Male
  • Middle Aged
  • Risk Factors
  • Smoking
  • Tunica Intima / pathology

Substances

  • Cholesterol, HDL
  • Hypolipidemic Agents