Raynaud's phenomenon of the lung. A reality both in primary and secondary Raynaud syndrome

Chest. 1992 May;101(5):1312-7. doi: 10.1378/chest.101.5.1312.


Vasospasm of RP is thought to occur in the lungs. To assess pulmonary vasospasm, we analyzed the early and late Dsb variations after a digital CPT. Sixteen normal volunteers and 20 patients (7 with primary, 13 with secondary RP) were included. A clinical RP was conducted on ten patients, nine with secondary and one with primary RP. The Dsb analysis showed: no significant variations in control subjects, a quick and short fall in primary RP significant after 15 min and a delayed fall in secondary RP significant after 45 min. A Dsb decrease was noticed even if no clinical RP occurred. The pallor phase of RP was associated with a concomitant decrease in the DCO and the hyperemic phase, with a Dsb increase. These results agree with those of previous studies with a few differences.

MeSH terms

  • Adult
  • Aged
  • Carbon Dioxide / physiology
  • Cold Temperature
  • Female
  • Forced Expiratory Volume
  • Humans
  • Lung Diseases / physiopathology*
  • Male
  • Middle Aged
  • Pulmonary Diffusing Capacity
  • Raynaud Disease / etiology
  • Raynaud Disease / physiopathology*
  • Total Lung Capacity
  • Vital Capacity


  • Carbon Dioxide