Pulmonary anisakiasis presenting as eosinophilic pleural effusion

Respirology. 2005 Mar;10(2):261-2. doi: 10.1111/j.1440-1843.2005.00643.x.


A 63-year-old man developed a pleural effusion with marked eosinophilia, which was more prominent in the pleural fluid than in the peripheral blood. The pleural effusion spontaneously disappeared 7 days after admission. A multiple dot enzyme-linked immunosorbent assay for anisakiasis was strongly positive for both the serum and pleural fluid. The serum IgG titre for Anisakis simplex gradually decreased over 7 months. It is suspected that Anisakis larvae can penetrate the alimentary canal, and then migrate into the pleural cavity through the diaphragm. Screening with a serological test is useful in the diagnosis of this condition; human pulmonary anisakiasis.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Anisakiasis / complications*
  • Anisakiasis / diagnosis
  • Anisakis / immunology
  • Diagnosis, Differential
  • Enzyme-Linked Immunosorbent Assay
  • Eosinophilia / diagnosis
  • Eosinophilia / etiology*
  • Humans
  • Immunoglobulin E / blood
  • Immunoglobulin G / blood
  • Lung Diseases, Parasitic / complications*
  • Lung Diseases, Parasitic / diagnosis
  • Male
  • Middle Aged
  • Pleural Effusion / diagnosis
  • Pleural Effusion / etiology*


  • Immunoglobulin G
  • Immunoglobulin E