Daptomycin-resistant, Methicillin-Resistant Staphylococcus Aureus Bacteremia

Clin Infect Dis. 2005 Apr 1;40(7):1058-60. doi: 10.1086/428616. Epub 2005 Feb 17.

Abstract

We describe a patient who developed daptomycin-resistant, methicillin-resistant Staphylococcus aureus (MRSA) during an episode of presumed septic thrombophlebitis of the portal vein. Although daptomycin is an alternative agent for treatment of drug-resistant gram-positive bacterial infections, development of resistance during prolonged use may occur with MRSA bacteremia from a persistent focus.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Bacterial Agents
  • Bacteremia / microbiology*
  • Daptomycin / pharmacology*
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Male
  • Methicillin Resistance
  • Middle Aged
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Daptomycin