Abstract
We describe a patient who developed daptomycin-resistant, methicillin-resistant Staphylococcus aureus (MRSA) during an episode of presumed septic thrombophlebitis of the portal vein. Although daptomycin is an alternative agent for treatment of drug-resistant gram-positive bacterial infections, development of resistance during prolonged use may occur with MRSA bacteremia from a persistent focus.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anti-Bacterial Agents
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Bacteremia / microbiology*
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Daptomycin / pharmacology*
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Drug Resistance, Multiple, Bacterial
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Humans
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Male
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Methicillin Resistance
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Middle Aged
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Staphylococcal Infections / drug therapy
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Staphylococcal Infections / microbiology*
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / isolation & purification
Substances
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Anti-Bacterial Agents
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Daptomycin