Serum cholesterol and testicular cancer incidence in 45,000 men followed for 25 years

Br J Cancer. 2005 May 9;92(9):1785-6. doi: 10.1038/sj.bjc.6602539.

Abstract

In a 25-year follow-up study of 44,864 men with measured serum cholesterol levels, the testicular cancer hazard ratios for the serum cholesterol categories 5.7-6.9 and > or = 7.0 mmol l(-1) vs the reference category (<5.7 mmol l(-1)) were 1.3 and 4.5, respectively; P-value for trend=0.005. This highly significant association suggests that high-serum cholesterol is a risk factor for testicular cancer.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cholesterol / blood*
  • Cohort Studies
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Risk Factors
  • Testicular Neoplasms / epidemiology*

Substances

  • Cholesterol